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Ataxin-1 (phospho Ser776) rabbit pAb

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  • 公司名稱 上海貝博生物科技有限公司
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  • 廠商性質(zhì) 生產(chǎn)廠家
  • 更新時(shí)間 2025/7/30 17:09:10
  • 訪問次數(shù) 44

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        貝博生物專注于生命科學(xué)研究用試劑產(chǎn)品的研究、開發(fā)、市場(chǎng)推廣和技術(shù)服務(wù)。致力于為中國廣大客戶提供量身定制的科研用試劑產(chǎn)品和專業(yè)技術(shù)服務(wù),幫助科研人員加速生物領(lǐng)域的研究進(jìn)展。 貝博生物將以高品質(zhì)的產(chǎn)品和服務(wù)打造中國*實(shí)力的試劑品牌。

      目前已上市了600多種蛋白提取試劑盒(動(dòng)物、植物、細(xì)菌、昆蟲、酵母等樣本及細(xì)胞器提取)及上千種的細(xì)胞檢測(cè)的相關(guān)產(chǎn)品-細(xì)胞凋亡、增殖毒性、細(xì)胞周期、膜電位檢測(cè)、細(xì)胞器熒光探針、活性氧ROS檢測(cè)、細(xì)胞自噬、細(xì)胞耗氧OCR、細(xì)胞外酸化率ECAR、缺氧檢測(cè)、粘附檢測(cè)、鈣離子檢測(cè)、膜通透性轉(zhuǎn)換孔檢測(cè)、膜流動(dòng)性檢測(cè)、外泌體、囊泡提取等。

 

蛋白提取,細(xì)胞分析

  • Source

    Rabbit

  • Applications

    WB,IHC,IF,ELISA

  • Reactivity

    Human,Mouse

  • Dilution

    WB: 1:500 - 1:2000. IHC: 1:100 - 1:300. IF: 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

  • Storage

    -20°C/1 year

  • Specificity

    Phospho-Ataxin-1 (S776) Polyclonal Antibody detects endogenous levels of Ataxin-1 protein only when phosphorylated at S776.

  • Source/Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen

    The antiserum was produced against synthesized peptide derived from human Ataxin 1 around the phosphorylation site of Ser776. AA range:742-791

  • Uniprot No

    P54253

  • Alternative names

    ATXN1; ATX1; SCA1; Ataxin-1; Spinocerebellar ataxia type 1 protein

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    ataxin 1(ATXN1) Homo sapiens The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. ADCAI is genetically heterogeneous, with five genetic loci, designated spinocerebellar ataxia (SCA) 1, 2, 3, 4 and 6, being assigned to five different chromosomes. ADCAII, which always presents with retinal degeneration (SCA7), and ADCAIII often referred to as the `pure' cerebellar syndrome (SCA5), are most likely homogeneous disorders. Several SCA genes have been cloned and shown to contain CAG repeats in their coding regions. ADCA is caused by the expansion of the CAG repeats, producing an elongated polyglutamine tract in the corresponding protein. The expanded repeats are variable in size and unstable, usually increasing in size when transmitted

  • Other

    ATXN1, Ataxin-1

  • Mol.Wt (Da)

    87051

  • Concentration

    1 mg/ml

Product Reactivity Applications Conjugation Catalog Images


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