2011 年，《自然方法》雜志（ Nature Methods ）將單細(xì)胞測(cè)序列為年度值得期待的技術(shù)之一，2013 年，《科學(xué)》雜志（Science）將單細(xì)胞測(cè)序列為年度Z值得關(guān)注的六大領(lǐng)域，表明單細(xì)胞測(cè)序已成為科研熱點(diǎn)。 應(yīng)廣大客戶(hù)的強(qiáng)烈需求，英國(guó)Dolomite公司成功研發(fā)出高通量RNA-seq轉(zhuǎn)錄組測(cè)序微流控系統(tǒng)，并成功完成了實(shí)驗(yàn)，發(fā)行了應(yīng)用報(bào)告。

(Macosko E., et al. "Highly Parallel Genome-wide Expression
Profiling of Individual Cells Using Nanoliter Droplets." Cell 161:1202

Tens of thousands of single cells are encapsulated with uniquely barcoded mRNA-capture beads. The cells are lysed in the droplets, and beads capture mRNA from single cells. The single cell RNA-beads are recovered and processed for downstream high throughput sequencing.