StemRD W5A-M-100 Mouse WNT Proteins WNT-5a 小鼠 WNT 蛋白因子，100ug

產品英文名稱：StemRD W5A-H-100 WNT-5a,mouse,100ug
產品中文名稱：StemRD W5A-H-100 小鼠WNT-5a 蛋白因子，100ug

StemRD W5A-H-100 WNT-5a,mouse,100ug 產品簡介
wnt通路是細胞增殖分化的關鍵調控環(huán)節(jié)， 在胚胎發(fā)育和腫瘤發(fā)生中起著重要作用。wnt途徑參與了基因表達調節(jié)、 細胞遷移粘附、細胞極化等過程，同時還與其它信號通路存在交叉協(xié)同。Wnt/β-catenin通路在進化過程中高度保守，此通路的主要分子構成及相關調 控機制已得到基本闡明。對神經系統(tǒng)而言已有足夠證據顯示此通路參與了對神經前體細胞增殖， 分化以及決定細胞命運的調控。
Wnt-3a干細胞生長分化因子是Wnt基因家族中重要成員，zui近的一些研究發(fā)現， Wnt-3a信號蛋白對神經干細胞的定向分化的調控作用表現的十分明顯。小鼠WNT-3a 干細胞生長分化因子蛋白包含328個氨基酸。

StemRD W5A-H-100 小鼠WNT-5a 蛋白因子，100ug 產品特性
?StemRD W5A-H-100 小鼠WNT-5a 蛋白因子，100ug 干細胞生長分化因子活性經過NIH 3T3 細胞鑒定，純度高
? StemRD W5A-H-100 小鼠WNT-5a 蛋白因子，100ug 干細胞生長分化因子生物活性在NIH 3T3 細胞經過TCF報告基因實驗鑒定The EC50為 50–150 ng/ml
? StemRD W5A-H-100 小鼠WNT-5a 蛋白因子，100ug 干細胞生長分化因子產品經過SDS-PAGE 和HPLC雙層鑒定純度大于90%

StemRD W5A-H-100 WNT-5a,mouse,100ug 保存方法
The lyophilized protein is stable for at least 6 months if stored at -80 degreeC. Reconstituted protein is stable for at least two weeks at 4 degree C, but should be stored in aliquots at -80 degree C for longer term. Avoid repeated freeze and thaw.

StemRD W5A-H-100 WNT-5a,mouse,100ug 產品英文描述
WNT-3a is a member of the WNT family of signaling proteins that play a key role in embryonic development and the integrity of adult tissues. StemRD W5A-H-100 WNT-5a,mouse,100ug is a prototypic canonical WNT that signals through the β-catenin pathway. The predicted size of mouse StemRD W5A-H-100 WNT-5a,mouse,100ug is a monomeric protein containing 333 amino acid residues. Due to glycosylation, it migrates at an apparent molecular weight of 40 kDa by SDS-PAGE analysis under nonreducing conditions. StemRD’s product W5A-H-100 WNT-5a,mouse,100ug is expressed from a mouse cell line overexpressing mouse WNT-3a. Purification is performed with a proprietary process that is distinct from the published method.
?StemRD W5A-H-100 WNT-5a,mouse,100ug Purity: Greater than 90% as determined by SDS-PAGE analysis
?StemRD W5A-H-100 WNT-5a,mouse,100ug Biological Activity: The activity was determined by using a TCF reporter gene assay in NIH3T3 cells. The EC50 ranges from 50 - 150 ng/ml. Country of Origin USA。

重慶市華雅干細胞技術有限公司