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南京科佰生物科技有限公司
主營(yíng)產(chǎn)品: atcc代理,ATCC細(xì)胞系,ATCC細(xì)胞株,ATCC細(xì)胞庫(kù)購(gòu)買 |
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南京科佰生物科技有限公司
主營(yíng)產(chǎn)品: atcc代理,ATCC細(xì)胞系,ATCC細(xì)胞株,ATCC細(xì)胞庫(kù)購(gòu)買 |
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參考價(jià) | 面議 |
更新時(shí)間:2022-04-28 17:21:12瀏覽次數(shù):596
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供貨周期 | 現(xiàn)貨 | 規(guī)格 | T-25 Flask |
---|---|---|---|
貨號(hào) | CBP73282 | 應(yīng)用領(lǐng)域 | 生物產(chǎn)業(yè) |
主要用途 | 僅限科研使用 |
CBP73282 | |
I. Introduction | |
Cell Line Name: | c-Kit D816H/BaF3 |
Host Cell: | Ba/F3 |
Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Application: | Anti-proliferation assay and PD assay |
Freeze Medium: | 90% FBS+10% DMSO |
Complete Culture Medium: | RPMI-1640+10%FBS |
Mycoplasma Status: | Negative |
II.Background | |
KIT D816H lies within the tyrosine kinase domain region 2 (exon 17) of the Kit protein (PMID: 19164557). D816H results in increased kinase activity, constitutive Kit phosphorylation, activation of Stat3 signaling, and transformation of cultured cells (PMID: 10362788, PMID: 11494148), and confers resistance to some Kit inhibitors (PMID: 25239608). | |
III. Representative Data | |
1. WB of c-Kit D816H/BaF3 | |
2. Sanger of c-Kit D816H/BaF3 | |
3. Anti-proliferation assay Figure 3. CTG Proliferation Assay of BaF3 C-KlT D816H. |