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南京科佰生物科技有限公司
主營產(chǎn)品： atcc代理,ATCC細(xì)胞系,ATCC細(xì)胞株,ATCC細(xì)胞庫購買 |
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聯(lián)系電話
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南京科佰生物科技有限公司
主營產(chǎn)品： atcc代理,ATCC細(xì)胞系,ATCC細(xì)胞株,ATCC細(xì)胞庫購買 |
聯(lián)系電話
| 參考價 | 面議 |
更新時間：2022-08-01 17:05:37瀏覽次數(shù)：775
聯(lián)系我們時請說明是化工儀器網(wǎng)上看到的信息，謝謝!
| 供貨周期 | 現(xiàn)貨 | 規(guī)格 | T-25 Flask |
|---|---|---|---|
| 貨號 | CBP73215 | 應(yīng)用領(lǐng)域 | 生物產(chǎn)業(yè) |
| 主要用途 | 僅限科研使用 |
CCDC6-RET V804L/BaF3激酶細(xì)胞 CBP73215 | |
| I. Introduction | |
Cell Line Name： | CCDC6-RET [V804L]/BaF3 |
Host Cell: | BA/F3 |
| Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Application: | Anti-proliferation assay and PD assay |
Freeze Medium: | 90% FBS+10% DMSO |
Complete Culture Medium: | RPMI-1640+10%FBS+1ug/ml puromycin |
Mycoplasma Status: | Negative |
| II.Background | |
CCDC6, coiled-coil domain containing 6, has been shown to play a role in the DNA damaging signaling pathway acting as a substrate of ATM (PMID: 17420723). CCDC6 fusions with RET (PMID: 23154560, PMID: 26078337) and BRAF (PMID: 26314551) have been observed in multiple cancer types. | |
| III. Representative Data | |
1.WB of CCDC6-RET V804L/BaF3
| |
2. Sanger of CCDC6-RET [V804L]/BaF3 | |
Figure 2. Breakpoint of CCDC6-RET V804L/BaF3 | |
Figure 3. Point mutation of CCDC6-RET V804L/BaF3 | |
| 3. Anti-proliferation assay | |
Figure 4. Anti-proliferation assay of one reference compounds on the CCDC6-RET V804L/BaF3 Stable Cell Line. | |
