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18066071954

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公司信息

聯(lián)人:
蔣經(jīng)理
話:
4008750250
機(jī):
18066071954
真:
址:
南京市棲霞區(qū)緯地路9號(hào)
編:
210000
個(gè)化:
www.co-bioer.com
網(wǎng)址:
www.cobioer.com/
鋪:
http://m.true-witness.com/st281842/
給他留言
CBP74048CSF1R/HEK293
CSF1R/HEK293
參考價(jià) 面議
具體成交價(jià)以合同協(xié)議為準(zhǔn)
  • 型號(hào) CBP74048
  • 品牌 cobioer/科佰生物
  • 廠商性質(zhì) 代理商
  • 所在地 南京市

更新時(shí)間:2022-07-29 14:08:07瀏覽次數(shù):668

聯(lián)系我們時(shí)請說明是化工儀器網(wǎng)上看到的信息,謝謝!

【簡單介紹】
供貨周期 現(xiàn)貨 規(guī)格 T-25 Flask
貨號(hào) CBP74048 應(yīng)用領(lǐng)域 生物產(chǎn)業(yè)
主要用途 僅限科研使用
CSF1R/HEK293,凍存條件:90% FBS+10% DMSO
【詳細(xì)說明】


CBP74048
I. Background
Colony Stimulating Factor 1 Receptor (CSF1R, CSFR, CD115, M-CSF-R) is a single-pass tyrosine kinase transmembrane receptor which is part of the type III protein tyrosine kinase receptor family. CSF1R is activated by either of two cytokines, CSF1 (MCSF; CSF-1) and IL-34 (IL34), causing homodimerization and activation of downstream kinase activity. CSF1R is expressed on the surface of monocytes and macrophages, and its activation controls the growth, function, and differentiation of macrophages. This interaction is used by numerous cancer types, such as diffuse-type tenosynovial giant cell tumors (dt-GCT), to evade the immune system. By overexpressing the cytokine CSF1, these cells drive the development and survival of Tumor-Associated Macrophages (TAMs), which in turn suppress the local immune response to the cancer.

II. Description
Recombinant HEK293 stably expressing human CSF1R (full-length human CSF1R cDNA (NP_005202) ).

III. Introduction
Host Cell:HEK293
Expressed gene:CSF1R
Stability:32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Synonym(s):CSF1R, CSFR, CD115, M-CSF-R
Freeze Medium:90% FBS+10% DMSO
Culture Medium:

DMEM+10%FBS+1ug/ml puromycin

Mycoplasma Testing:Negative
Storage:Liquid nitrogen.
Application(s):Binding Assay,FACS

IV. Description of Host Cell Line
Organism:Homo sapiens,human
Tissue:Embryonic kidney
Disease: Normal
Morphology: Epitheloid cell
Growth Properties: Adherent

Ⅴ. Representative Data

CBP74048.png


Figure 1. Recombinant HEK293 stably expressing human CSF1R (full-length human CSF1R cDNA (NP_005202) ).






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