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南京科佰生物科技有限公司
主營產(chǎn)品: atcc代理,ATCC細(xì)胞系,ATCC細(xì)胞株,ATCC細(xì)胞庫購買 |
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南京科佰生物科技有限公司
主營產(chǎn)品: atcc代理,ATCC細(xì)胞系,ATCC細(xì)胞株,ATCC細(xì)胞庫購買 |
聯(lián)系電話
參考價(jià) | 面議 |
更新時(shí)間:2022-09-15 12:01:51瀏覽次數(shù):461
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供貨周期 | 現(xiàn)貨 | 規(guī)格 | 1ug |
---|---|---|---|
貨號(hào) | CBP10434 | 應(yīng)用領(lǐng)域 | 生物產(chǎn)業(yè) |
CBP10434 | |
Gene | CDKN2A |
Description | CDKN2A, cyclin-dependent kinase inhibitor 2A, is a tumor suppressor (PMID: 30562755) that encodes p16 and p14ARF from alternate reading frames, which function to inhibit Cdk4 and Cdk6 and regulate Tp53 activity to promote cell-cycle arrest (PMID: 23875803, PMID: 17055429, PMID: 27428416). CDKN2A germline mutations are associated with familial atypical multiple mole melanoma and somatic mutations are highest in pancreatic, HNSCC, NSCLC, and melanoma (PMID: 27283171). |
Technical Data | |
DNA Change | c.37_49del |
AA Change | p.ATAAA17f |
Mutation type | Frame_Shift_Del |
Zygosity | Heterozygous |
Allelic Frequency | 50.00% |
Transcript | ENST00000304494.5 |
Cosmic ID | N/A |
Chr position(GRCh37) | chr9:21974790_21974778 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |