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Insulin-Like Growth Factor Binding Protein 3 (IGFB

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Insulin-Like Growth Factor Binding Protein 3 (IGFBP3) 抗體的概念:
Z初有人用電泳證明血清中抗體活性在γ球蛋白部分,故曾把抗體統(tǒng)稱為丙種(γ)球蛋白。后來發(fā)現(xiàn),抗體并不都在γ區(qū);并且位于γ區(qū)的球蛋白,也不一定都具有抗體活性,規(guī)格:0.1ml/100µg、0.2ml/200µg

Insulin-Like Growth Factor Binding Protein 3 (IGFBP3) 抗體

抗原
Insulin-Like Growth Factor Binding Protein 3 (IGFBP3)
別名 IGFBP-3, zgc:91788, IGFBP3, igfbp3, BP-53, IBP3, AI649005, IGgfbp3, IGF-BP3
適用
其他選擇 Human
Human(112),Murine (42),Rat ((Rattus)) (24),Dog (Canine) (2),Bovine (1),Hamster (1)
宿主
其他選擇 Mouse
Rabbit(106),Mouse (14),Goat (6),Rat (1)
克隆類型 (克隆位點)
單克隆 (83-8F9)
標記
其他選擇 非結(jié)合性
Biotin(10),FITC (5),HRP (3),APC (2),Alkaline Phosphatase (AP) (2),PE (2),Alexa Fluor 350 (1),Alexa Fluor 488 (1),Alexa Fluor 555 (1),Alexa Fluor 647 (1),Cy3 (1),Cy5 (1),Cy5.5 (1),Cy7 (1)
應(yīng)用范圍
其他選擇 Enzyme Immunoassay (EIA)
Western Blotting (WB)(93),ELISA (68),Immunohistochemistry (IHC) (45),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (22),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (10),Immunocytochemistry (ICC) (9),Enzyme Immunoassay (EIA) (7),Immunohistochemistry (Frozen Sections) (IHC (fro)) (7),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (3),Immunofluorescence (IF) (2),Immunoprecipitation (IP) (2),Blocking Antibody (Inhibition) (1),Immunoassay (IA) (1),Immunoradiometric Assay (IRMA) (1),Neutralization (Neut) (1),Radioimmunoassay (RIA) (1)
規(guī)格 0.5 mg
發(fā)貨至 中國 (更改)
發(fā)貨時間 29至35個工作日

Insulin-Like Growth Factor Binding Protein 3 (IGFBP3) 抗體

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產(chǎn)品細節(jié)

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免疫原 Recombinant human IGFBP-3
克隆位點 83-8F9
亞型 IgG1
特異性 This antibody recognizes IGFBP-3.
產(chǎn)品特性 Synonyms: IGFBP-3, IGF-BP3, IBP3, Insulin-like growth factor-binding protein 3, IGF-binding protein 3,IBP-3
純化方法 Purified IgG prepared by affinity chromatography on Protein A

Insulin-Like Growth Factor Binding Protein 3 (IGFBP3) 抗體目標詳細情況

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目標詳細情況

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別名 IGFBP3
背景 IGFBP-3 is a member of the superfamily of insulin-like growth factor binding proteins that hold a central position in IGF ligand-receptor interactions through influences on both the bioavailability and distribution of IGFs in the extracellular environment. IGFBP-3 is found in human serum and has two forms of approximate molecular mass 40 and 43 kDa. IGFBP-3 binds IGF-1 and IGF-2 with similar high affinity. In the blood stream, approximay 90?% of IGFBP-3 is found in a ternary complex of 140 kDa. This complex comprises an acid-labile subunit (alpha-subunit), IGFBP-3 (beta-subunit) and IGF-1 or IGF-2. This binding prolongs the metabolic half-life of IGF-1 in circulation and serves as a metabolic reservoir of IGF-1.Synonyms: IBP-3, IBP3, IGF-BP3, IGF-binding protein 3, IGFBP-3, Insulin-like growth factor-binding protein 3
基因ID 3486
UniProt P17936
研究領(lǐng)域 Cardiovascular, Atherosclerosis, Angiogenesis, Apoptosis/Necrosis, Hormones, Diabetes, Metabolism, Growth Factors

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應(yīng)用備注 ELISA. IRMA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
限制 For Research Use only

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貯存及處理

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濃度 1.0 mg/mL
緩沖液 Phosphate buffered saline,?pH 7.4 containing 0.09?% Sodium Azide (NaN3)
儲存液 Sodium azide
注意事項 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
儲存條件 4 °C/-20 °C
儲存方法 Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. Caution: (A full Health and Safety assessment is available upon request) This product containsSodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled bytrained staff only.
有效期 12 months

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