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抗原
Jagged 1 (JAG1)
別名 JAG1, AGS, AHD, AWS, CD339, HJ1, JAGL1, ABE2, Gsfabe2, Htu, Ozz, Ser-1
抗原表位
其他選擇 Internal Region
AA 1129-1158(8),C-Term (8),AA 110-125 (7),AA 1-1046 (4),AA 1204-1218 (2),AA 32-296 (2),AA 33-250 (2),AA 469-746 (2),AA 531-620 (2),AA 905-1014 (2),Extracellular Domain (2),AA 1-1218 (1),AA 1-296 (1),AA 1168-1218 (1),AA 470-834 (1),AA 531-621 (1),AA 826-1084 (1),AA 836-1047 (1),AA 886-1218 (1),Internal Region (1)
適用
其他選擇 Human, Murine
Human(68),Murine (26),Rat ((Rattus)) (18),Chimpanzee (2)
宿主
其他選擇 Rabbit
Rabbit(48),Mouse (19),Hamster (6),Goat (3),Armenian Hamster (2),Rat (1)
克隆類型
多克隆
標記
其他選擇 非結(jié)合性
PE(6),FITC (5),Biotin (3),APC (2),HRP (2),Alexa Fluor 350 (1),Alexa Fluor 488 (1),Alexa Fluor 555 (1),Alexa Fluor 647 (1),Alkaline Phosphatase (AP) (1),CF (1),Cy3 (1),Cy5 (1),Cy5.5 (1),Cy7 (1),PerCP (1)
應(yīng)用范圍
其他選擇 Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Fluorescence Microscopy (FM)
Western Blotting (WB)(48),ELISA (37),Flow Cytometry (FACS) (30),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (15),Immunohistochemistry (IHC) (11),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (10),Immunocytochemistry (ICC) (9),Immunofluorescence (IF) (8),Immunohistochemistry (Frozen Sections) (IHC (fro)) (8),Enzyme Immunoassay (EIA) (3),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (2),Immunoprecipitation (IP) (2),Neutralization (Neut) (2),Fluorescence Microscopy (FM) (1),Immunoassay (IA) (1)
[Pubmed] 1 reference available
規(guī)格 25 μL
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JAG1抗體
產(chǎn)品細節(jié)
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免疫原 This protein A purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 110-125 of human Jagged-1protein.
Immunogen Type: Peptide
亞型 IgG
特異性 This protein A purified antibody is directed against human Jagged-1 protein. The product was purified from mono-specific antiserum by affinity chromatography. A BLAST analysis was used to suggest cross reactivity with Jagged-1 protein from human, chimpanzee, rat and mouse based on 100% homology with the immunizing sequence. Partial reactivity is expected against dog (81%) and Xenopus laevis (85%) based on partial sequence homologies as indicated. Reactivity against homologues from other sources is not known.
產(chǎn)品特性 Anti Jagged 1 Antibody recognizes the jagged 1 protein encoded by the JAG1 gene, that is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signaling through notch 1 has also been shown to play a role in hematopoies.
純化方法 purified
過濾 Sterile filtered
目標詳細情況
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目標詳細情況
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別名 Jagged 1
背景 Anti Jagged 1 Antibody recognizes the jagged 1 protein encoded by the JAG1 gene, that is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signaling through notch 1 has also been shown to play a role in hematopoies.
Synonyms: Ser 1 antibody, AGS antibody, AHD antibody, AWS antibody, CD 339 antibody, CD339 antibody, CD339 antigen antibody, Headturner antibody, HJ1 antibody, Htu antibody
基因ID 182, 4557679
UniProt P78504
使用細節(jié)
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使用細節(jié)
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應(yīng)用備注 This protein A purified antibody has been tested for use in ELISA, immunohistochemistry, immunofluorescence microscopy and western blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximay 150 kDa in size corresponding to Jagged-1 in mouse liver whole cell lysates, and a 75 kDa band in human brain and kidney lysates.
說明
Gene Name: JAG1
限制 For Research Use only
貯存及處理
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貯存及處理
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狀態(tài) Liquid
濃度 1.1 mg/mL
緩沖液 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
儲存液 Sodium azide
注意事項 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
儲存條件 4 °C/-20 °C
儲存方法 Store vial at 4° C prior to restoration. For extended storage aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Centrifuge product if not compley clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.
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