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GRM3抗體

抗原
Glutamate Receptor, Metabotropic 3 (GRM3)
別名 GLUR3, GPRC1C, MGLUR3, mGlu3, 0710001G23Rik, Gprc1c, mGluR3
抗原表位
其他選擇 C-Term, AA 828-857
C-Term(15),N-Term (12),AA 833-863 (6),Extracellular Domain (3),AA 118-126 (2),AA 24-38 (2),Extracellular Loop (2),AA 21-120 (1),AA 25-507 (1),AA 815-829 (1),AA 815-879 (1),AA 828-857 (1)
適用
其他選擇 Human
Human(65),Rat ((Rattus)) (40),Murine (38),Bovine (27),Chicken (13),Dog (Canine) (13)
宿主
其他選擇 Rabbit
Rabbit(67),Chicken (1),Mouse (1),Sheep (1)
克隆類型 (克隆位點)
多克隆 (RB4623)
標記
其他選擇 非結(jié)合性
Biotin(3),FITC (3),HRP (3),PE (3),Alexa Fluor 350 (2),Alexa Fluor 488 (2),Alexa Fluor 555 (2),Alexa Fluor 647 (2),Cy3 (2),Cy5 (2),Cy5.5 (2),Cy7 (2),APC (1),Alkaline Phosphatase (AP) (1)
應用范圍
其他選擇 Western Blotting (WB)
Western Blotting (WB)(42),Flow Cytometry (FACS) (22),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (20),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (18),Immunohistochemistry (IHC) (15),ELISA (14),Immunocytochemistry (ICC) (9),Immunofluorescence (IF) (5),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (2),Immunohistochemistry (Frozen Sections) (IHC (fro)) (2),Immunoprecipitation (IP) (2),Enzyme Immunoassay (EIA) (1)
[Pubmed] 5 references available
規(guī)格 400 μL
發(fā)貨至 中國 (更改)
發(fā)貨時間 9至13個工作日

GRM3抗體

產(chǎn)品細節(jié)

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產(chǎn)品細節(jié)

顯示 隱藏
免疫原 This Metabotropic Glutamate Receptor 3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 828-857 AA from the C-terminal region of human Metabotropic Glutamate Receptor 3.
克隆位點 RB4623
亞型 Ig
特異性 This Metabotropic Glutamate Receptor 3 Antibody antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 833~863 amino acids from the C-terminal region of human GPRC1C.
預測反應 Monkey
純化方法 This antibody is purified through a protein A column, followed by peptide affinity purification.

目標詳細情況

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目標詳細情況

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別名 Metabotropic Glutamate Receptor 3 (GPRC1C)
背景 L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 (also known as GPRC1C) while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. The activity of GRM3 is mediated by a G-protein that inhibits adenylate cyclase activity.
Synonyms: Metabotropic glutamate receptor 3 [Precursor], mGluR3, GRM3, GPRC1C, MGLUR3,
分子量 98879 DA
基因ID 2913
UniProt Q14832
研究領域 Cell Signaling, Neurology, Cell Structure

使用細節(jié)

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使用細節(jié)

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應用備注 WB = 1:1000
限制 For Research Use only

貯存及處理

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貯存及處理

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狀態(tài) Liquid
濃度 0.43 mg/mL
緩沖液 PBS with 0.09 % (W/V) sodium azide
儲存液 Sodium azide
注意事項 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
儲存條件 4 °C/-20 °C
儲存方法 Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
有效期 6 months

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