FEN1抗體 返回列表頁

FEN1抗體

抗原
Flap Structure-Specific Endonuclease 1 (FEN1)
別名 FEN-1, FEN1, AW538437, MF1, RAD2, cb879, fen-1, fen1, mf1, rad2, xFEN1a
抗原表位
其他選擇 AA 243-272, Center
N-Term(8),C-Term (6),AA 1-380 (4),Internal Region (4),AA 1-110 (2),AA 250-300 (2),AA 1-111 (1),AA 1-188 (1),AA 169-380 (1),AA 243-272 (1),AA 300-330 (1),AA 75-125 (1),AA 86-135 (1),Ala119 (1),Center (1)
適用
其他選擇 Human
Human(77),Murine (37),Rat ((Rattus)) (34),Dog (Canine) (14),Bovine (13),Pig (Porcine) (12),Chicken (1),Rat (Meriones) (1),Xenopus laevis (1),Zebrafish (Danio rerio) (1)
宿主
其他選擇 Rabbit
Rabbit(65),Mouse (13)
克隆類型 (克隆位點(diǎn))
多克隆 (RB17639)
標(biāo)記
其他選擇 非結(jié)合性
Alexa Fluor 350(1),Alexa Fluor 488 (1),Alexa Fluor 555 (1),Alexa Fluor 647 (1),Biotin (1),Cy3 (1),Cy5 (1),Cy5.5 (1),Cy7 (1),FITC (1),HRP (1)
應(yīng)用范圍
其他選擇 Western Blotting (WB), Immunofluorescence (IF)
Western Blotting (WB)(66),Immunofluorescence (IF) (20),ELISA (18),Immunohistochemistry (IHC) (18),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (10),Immunoprecipitation (IP) (10),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (9),Immunocytochemistry (ICC) (8),Flow Cytometry (FACS) (3),Dot Blot (DB) (2),Immunoassay (IA) (2),Enzyme Immunoassay (EIA) (1),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (1)
[Pubmed] 3 references available
規(guī)格 400 μL
發(fā)貨至 中國(guó) (更改)
發(fā)貨時(shí)間 9至13個(gè)工作日

FEN1抗體

產(chǎn)品細(xì)節(jié)

引用 圖像 貯存及處理 使用細(xì)節(jié) 目標(biāo)詳細(xì)情況 回頁首

產(chǎn)品細(xì)節(jié)

顯示 隱藏
免疫原 This FEN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 243-272 AA from the Central region of human FEN1.
克隆位點(diǎn) RB17639
亞型 Ig
特異性 This FEN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 250~280 amino acids from the Center region of human FEN1.
預(yù)測(cè)反應(yīng) Cow (Bovine)
純化方法 This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

目標(biāo)詳細(xì)情況

引用 圖像 貯存及處理 使用細(xì)節(jié) 回頁首

目標(biāo)詳細(xì)情況

顯示 隱藏
別名 FEN1
背景 FEN1 removes 5' overhanging flaps in DNA repair and processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis. Direct physical interaction between this protein and AP endonuclease 1 during long-patch base excision repair provides coordinated loading of the proteins onto the substrate, thus passing the substrate from one enzyme to another. This protein is a member of the XPG/RAD2 endonuclease family and is one of ten proteins essential for cell-free DNA replication. DNA secondary structure can inhibit flap processing at certain trinucleotide repeats in a length-dependent manner by concealing the 5' end of the flap that is necessary for both binding and cleavage by the protein encoded by this gene. Therefore, secondary structure can deter the protective function of this protein, leading to site-specific trinucleotide expansions.
Synonyms: Flap endonuclease 1, Flap structure-specific endonuclease 1, Maturation factor 1, DNase IV, RAD2
Pathways: Base excision repair
分子量 42593 Da
基因ID 2237
UniProt P39748
研究領(lǐng)域 Stem Cells, Signaling, Chromatin

使用細(xì)節(jié)

引用 圖像 貯存及處理 目標(biāo)詳細(xì)情況 回頁首

使用細(xì)節(jié)

顯示 隱藏
應(yīng)用備注 IF = 1:100, WB = 1:1000
限制 For Research Use only

貯存及處理

引用 圖像 使用細(xì)節(jié) 目標(biāo)詳細(xì)情況 回頁首

貯存及處理

顯示 隱藏
狀態(tài) Liquid
濃度 2 mg/mL
緩沖液 PBS with 0.09 % (W/V) sodium azide
儲(chǔ)存液 Sodium azide
注意事項(xiàng) This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
儲(chǔ)存條件 4 °C/-20 °C
儲(chǔ)存方法 Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
有效期 6 monthsxy-15063R C1orf2291號(hào)染色體開放閱讀框229抗體
xy-2232R Cecropin殺菌肽/天蠶抗菌肽抗體
xy-3642R Cullin 4ACullin 4a蛋白抗體
xy-3646R CK3細(xì)胞角蛋白3抗體
xy-15209R C5orf525號(hào)染色體開放閱讀框52抗體
xy-10390R CCDC85B卷曲螺旋結(jié)構(gòu)域蛋白85B抗體
xy-5025R Claudin 14緊密連接蛋白14抗體
xym-2271M CMV(1F11)人巨細(xì)胞病毒單克隆抗體
xy-0719R CEA癌胚抗原抗體
xy-2209R CXCR3細(xì)胞表面趨化因子受體3抗體
xy-15064R C1orf331號(hào)染色體開放閱讀框33抗體
xy-3061R Phospho-CEBP alpha (Thr222 + Thr226)磷酸化轉(zhuǎn)錄調(diào)節(jié)因子CEBP α 抗體
xy-3062R Phospho-CEBP beta (Ser105)磷酸化轉(zhuǎn)錄調(diào)節(jié)因子CEBP β抗體
xy-3063R Phospho-CEBP beta (Thr235)磷酸化轉(zhuǎn)錄調(diào)節(jié)因子CEBP β抗體
xy-3264R Phospho-CD18 (Ser756 + Thr758 + Thr759)磷酸化整合素β2/Integrin β2抗體
xy-3065R Phospho-CD19 (Tyr531)磷酸化CD19抗體
xy-2753R CENPA著絲粒蛋白A
xy-3066R Phospho-CENPA (Ser7)磷酸化著絲粒蛋白A
xy-3068R Phospho-CRMP2 (Thr514)磷酸化二氫嘧啶酶樣2抗體
xy-1487R CC16克拉拉細(xì)胞蛋白抗體
xy-1481R CD22B淋巴細(xì)胞粘附分子CD22抗體
xy-1598R Cathepsin G組織蛋白酶G抗體
xy-1479R CD80刺激分子B7-1蛋白抗體
xy-15023R C1orf1451號(hào)染色體開放閱讀框145抗體
xy-15102R C20orf18620號(hào)染色體開放閱讀框186抗體
xy-1610R CK7細(xì)胞角蛋白7抗體
xy-1715R Connexin 26間隙連接蛋白26抗體
xy-1529R CD46/MCP膜輔蛋白抗體
xy-5161R CAPZA1F肌動(dòng)蛋白α1亞基抗體
xy-4790R CD8CD8抗體