細胞粘附分子伴侶蛋白2抗體 返回列表頁

細胞粘附分子伴侶蛋白2抗體

英文名稱 Sidekick 2
中文名稱 細胞粘附分子伴侶蛋白2抗體
別    名 SDK2; SDK 2; SDK-2; SDK2; Sidekick 2; Sidekick homolog 2 (chicken); sidekick-2; Sidekick2; FLJ10832; KIAA1514; SDK2_HUMAN.

說 明 書 0.1ml  0.2ml  
研究領域 細胞生物  神經(jīng)生物學  細胞粘附分子  細胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep, 
產(chǎn)品應用 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 237kDa
細胞定位 細胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Sidekick 2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
Sidekick-2 (SDK2), also known as KIAA1514, is a 2,172 amino acid single-pass type I membrane protein containing thirteen fibronectin type-III domains and six Ig-like C2-type (immunoglobulin-like) domains. Acting as a cell adhesion protein, Sidekick-2 guides axonal terminals to synapses in developing neurons. Sidekick-2 may require the interaction with MAGI scaffolding proteins for proper localization and function. Existing as four alternatively spliced isoforms, the gene encoding Sidekick-2 maps to human chromosome 17q25.1. Chromosome 17 makes up over 2.5% of the human genome with about 81 million bases encoding over 1,200 genes. Neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth have been linked to chromosome 17. Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17.

Function:
Sidekick 2 is a cell adhesion protein that guides axonal terminals to specific synapses in developing neurons.xy-6780R    TYRO3受體酪氨酸激酶抗體
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