滑膜肉瘤X染色體相關2抗體 返回列表頁

滑膜肉瘤X染色體相關2抗體

英文名稱 SSX2
中文名稱 滑膜肉瘤X染色體相關2抗體
別    名 CT5.2; X breakpoint 2; Cancer/testis antigen 5.2; CT5.2; HD21; hom mel 40; HOM-MEL-40; MGC119055; Protein SSX2; RP11-552J9.2; sarcoma, synovial, X-chromosome related 2; SSx; SSX2; SSX2-SYT fusion gene, included; SSX2_HUMAN; SSX2B; Synovial sarcoma; synovial sarcoma X breakpoint 2; Tumor antigen HOM-MEL-40.
  
說 明 書 0.1ml  0.2ml  
研究領域 腫瘤  細胞生物  轉錄調節(jié)因子  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, 
產品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 22kDa
細胞定位 細胞核 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SSX2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產品介紹 background:
The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneous humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. This gene, and also the SSX1 and SSX4 family members, have been involved in t(X;18)(p11.2;q11.2) translocations that are characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are likely responsible for transforming activity. Alternative splicing of this gene results in multiple transcript variants. This gene also has an identical duplicate, GeneID: 727837, located about 45 kb downstream in the opposite orientation on chromosome X. [provided by RefSeq, Jul 2013]

Function:
Could act as a modulator of transcription. 

Subunit:
Interacts via its N-terminal region with RAB3IP and SSX2IP.

Subcellular Location:xy-7618R    NOC2LNOC2家族樣蛋白抗體
xy-8551R    Nitrotyrosine硝基酪氨酸抗體
xy-7106R    NUPR1核蛋白p8抗體
xy-7644R    NSPL2神經內分泌特異性蛋白2抗體
xy-6845R    NOX5還原型輔酶Ⅱ氧化酶5/煙酰胺腺嘌呤二核苷酸磷酸抗體
xy-6846R    Nucleostemin核干細胞因子抗體(鳥嘌呤核苷酸結合蛋白3)
xy-6764R    NPC1尼曼匹克C1前體蛋白抗體
xy-6331R    NET1去甲腎上腺素轉運蛋白/神經遞質去甲腎上腺素轉運體抗體
xy-6555R    NUP88核孔復合體蛋白88抗體
xy-6554R    NOL8核仁蛋白8抗體
xy-4280R    Nck betaNCK銜接蛋白2抗體
xy-6597R    NPHS2腎小球裂孔膜蛋白PDCN抗體
xy-6563R    NMT1豆蔻?；D移酶1抗體
xy-7517R    Natriuretic Peptide Receptor A利鈉肽受體A抗體
xy-6235R    NRG3神經調節(jié)蛋白3抗體
xy-7813R    NEDD1神經前體細胞表達蛋白1抗體
xy-7814R    NEK1絲氨酸/蘇氨酸蛋白激酶NEK1抗體
xy-11593R    NAT8LN-乙酰轉移酶8樣蛋白抗體
xy-11443R    NMS神經調節(jié)肽S抗體
xy-11444R    Nocturnin分子生物鐘調控蛋白NOC抗體
xy-11465R    Neogenin神經細胞粘附蛋白NGN抗體
xy-11467R    Neuron navigator 1神經細胞蛋白Nav1抗體
xy-11468R    Nogo B receptor軸索過度生長抑制因子B受體抗體
xy-4311R    NR0B2核受體0相關蛋白B家族2抗體
xy-6125R    phospho-p95 NBS1 (Ser343)磷酸化DNA修復蛋白NBS1抗體
xy-4753R    ASP4天冬氨酸蛋白酶ASP4抗體
xy-6233R    NMT2肉豆蔻酰基轉移酶2-N端肽抗體
xy-4246R    NFAT1核因子活化T細胞胞漿蛋白2抗體
xy-4212R    Neuroligin 1突觸細胞粘附分子1抗體
xy-2935R    Nucleoporin p62核孔糖蛋白P62抗體
xy-4724R    NT-3神經營養(yǎng)因子3抗體
xy-8204R    NEEP21NEEP21蛋白抗體
xy-5382R    Phospho-NMDAR2B (Ser1480)磷酸化谷氨酸受體2B抗體