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SET結(jié)合蛋白1抗體

英文名稱(chēng) SETBP1
中文名稱(chēng) SET結(jié)合蛋白1抗體
別    名 SETBP_HUMAN; SET-binding protein; SEB; SET binding protein 1; SETBP-1; SETBP 1.
  
說(shuō) 明 書(shū) 0.2ml  
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 176kDa
細(xì)胞定位 細(xì)胞核 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SETBP1
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
SETBP1 (SET binding protein 1), also known as SEB, is a 1,542 amino acid nuclear protein that contains three AT hook DNA-binding domains, one SKI homology region and a C-terminal SET-binding domain, which is followed by three PPLPPPPP repeats. SETBP1 may be involved in SET-related tumorigenesis and leukemogenesis by regulating the transforming activity of SKI in the nucleus or suppressing SET function. As a widely expressed protein, SETBP1 is encoded by a gene that maps to human chromosome 18, which houses over 300 protein-coding genes and contains nearly 76 million bases. There are a variety of diseases associated with defects in chromosome 18-localized genes, some of which include Trisomy 18 (also known as Edwards syndrome), Niemann-Pick disease, hereditary hemorrhagic angiectasia, erythropoietic protoporphyria and follicular lymphomas.

Subunit:
Interacts with SET.

Subcellular Location:
Nucleus.xy-5540R    phospho-FAK(Tyr925)磷酸化粘著斑激酶抗體
xy-5541R    phospho-PTK2(Tyr576+Tyr577)磷酸化粘著斑激酶抗體
xy-5542R    phospho-PAK1(Thr212)磷酸化p21激活激酶1抗體
xy-5543R    Phospho-PDPK1(Tyr9)磷酸化3磷酸肌醇依賴(lài)性蛋白激酶1抗體
xy-5544R    Phospho-PDPK1(Ser396)磷酸化3磷酸肌醇依賴(lài)性蛋白激酶1抗體
xy-5545R    Phospho-PDPK1(Ser410)磷酸化3磷酸肌醇依賴(lài)性蛋白激酶1抗體
xy-5546R    Phospho-PLC gamma 1(Tyr775)磷酸化磷酯酶Cγ1抗體
xy-5547R    Phospho-PLC gamma 2(Tyr753)磷酸化磷酯酶Cγ2抗體
xy-5548R    Phospho-Paxillin(Tyr88)磷酸化樁蛋白Paxillin抗體
xy-5549R    Phospho-Paxillin(Ser83)磷酸化樁蛋白Paxillin抗體
xy-5550R    Phospho-Paxillin(Ser178)磷酸化樁蛋白Paxillin抗體
xy-2718R    phospho-PKC beta 1/2(Thr500)磷酸化蛋白激酶C β1/β2(Thr500)抗體
xy-5922R    PGRMC孕激素受體膜相關(guān)元件抗體
xy-3714R    Phospho-p63 (Ser395)磷酸化P63腫瘤抑制基因抗體
xy-3715R    Phospho-p63 (Ser455)磷酸化P63腫瘤抑制基因抗體
xy-5952R    POMT1蛋白甘露糖基轉(zhuǎn)移酶1抗體
xy-3497R    Phospho-p40phox (Thr154)磷酸化嗜中性粒細(xì)胞胞漿因子4抗體
xy-3617R    P70 Beta 2核糖體S6蛋白激酶β2抗體
xy-3498R    Phospho-p70 S6 Kinase Beta 2 (Tyr389)磷酸化核糖體S6蛋白激酶β2抗體
xy-3499R    Phospho-p70 S6 Kinase Beta (Thr228)磷酸化核糖體S6蛋白激酶β2抗體
xy-3700R    Phospho-p70 S6 Kinase Beta (Thr444 + Ser447)磷酸化核糖體S6蛋白激酶β2抗體
xy-3701R    phospho-P70 S6 Kinase beta 2 (Ser370)磷酸化核糖體S6K2蛋白激酶抗體
xy-3702R    phospho-P53(Ser15)磷酸化腫瘤抑制基因P53抗體
xy-3703R    phospho-P53(Ser20)磷酸化腫瘤抑制基因P53抗體
xy-3706R    phospho-P53(Ser37)磷酸化腫瘤抑制基因P53抗體
xy-3707R    phospho-P53(Ser46)磷酸化腫瘤抑制基因P53抗體
xy-3708R    phospho-P53(Ser6)磷酸化腫瘤抑制基因P53抗體
xy-3709R    phospho-P53 (Ser9)磷酸化腫瘤抑制基因P53抗體
xy-3710R    phospho-P53(Thr18)磷酸化腫瘤抑制基因P53抗體
xy-3711R    phospho-P53(Thr81)磷酸化腫瘤抑制基因P53抗體
xy-6147R    p73 alphap53相關(guān)蛋白P73α抗體
xy-6146R    p53 DINP1p53誘導(dǎo)核蛋白1抗體
xy-2944R    plant lectin B4植物凝集素IB4
xy-6143R    PIG3p53誘導(dǎo)蛋白3抗體
xy-6144R    PRMT4組蛋白精氨酸甲基轉(zhuǎn)移酶CARM1抗體
xy-5433R    PPAP2C磷酸脂磷酸水解酶2抗體
xy-4184R    p107視網(wǎng)膜母細(xì)胞瘤樣蛋白p107抗體
xy-5597R    phospho-P53(Ser376)磷酸化腫瘤抑制基因P53抗體
xy-6061R    PIGR多聚免疫球蛋白受體抗體