1,4,7,10-四氮雜環(huán)十二烷-1,4,7,10-四乙酸（DOTA）是一種大環(huán)絡合劑。通過螯合64銅放射性同位素，它已被用于碳納米管生物結合物的放射性標記。在臨床放射中，DOTA可被N-羥基磺基琥珀酰亞胺激活，與單克隆結合。

名稱：ACI

1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic acid

10-[2-[[3-[(2-Methyl-1-oxo-2-propen-1-yl)amino]propyl]amino]-2-oxoethyl]-1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid

CAS：1565798-78-8

化學式：C23H40N6O8

分子量：528.2908

結構式以及核磁圖譜：

LCMS分析報告：

產品簡介：1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA) is a macrocyclic complexing agent. It has been used for radiolabeling of carbon nanotube bioconjugates by chelating 64 Cu radioisotope. DOTA can be activated with N -hydroxysulfosuccinimidyl for conjugation with monoclonal antibodies in clinical radioimmunotherapy.

相關化合物：

1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic acid

217973-03-0

gadolinium(III) 1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid

112188-16-6

1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic acid, triMethyl ester

131934-31-1

10-phosphonomethyl-1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid

677335-18-1

1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic acid, 10-(2-aMinoethyl)-

114873-43-7

1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic Acid Tri-tert-butyl Ester

122555-91-3

1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic Acid Tri-tert-butyl Ester

18271-97-1

10-(3,6,9-trioxatridecyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid

686289-85-0

1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic acid, 1,4,7-tris(phenylmethyl) ester

957130-00-6

供應商：陜西新研博美生物科技有限公司

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