技術文章
CTTHWGFTLC, CYCLIC基質(zhì)金屬蛋白酶介紹
閱讀:130 發(fā)布時間:2022-4-8英文別名:CTTHWGFTLC, CYCLIC
h-cys-thr-thr-his-trp-gly-phe-thr-leu-cys-oh
H-Cys-Thr-Thr-His-Trp-Gly-Phe-Thr-Leu-Cys-OH (Disulfide bond)
CAS號:244082-19-7
分子式:C52H71N13O14S2
分子量:1166.33
結(jié)構(gòu)式:
***質(zhì)量:1165.47000
PSA:480.98000
LogP:0.56840
靶點:MMP-2;MMP-9
描述:CTTHWGFTLC, CYCLIC 是基質(zhì)金屬蛋白酶 MMP-2 和 MMP-9 的環(huán)肽抑制劑。
參考文獻:
[1]. Medina OP, et al. Binding of novel peptide inhibitors of type IV collagenases to phospholipid membranes and use in liposome targeting to tumor cells in vitro. Cancer Res. 2001 May 15;61(10):3978-85.
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