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MCE 國際站:Hydrocortisone
品牌:MedChemExpress (MCE)
CAS:50-23-7
純度:0.9991
貨號(hào):HY-N0583
中文名稱:氫化可的松;可的索;可的唑;皮質(zhì)醇;氫可的松;17-羥基皮質(zhì) (甾) 酮;皮質(zhì)甾醇;氫化皮質(zhì)素
Synonyms:氫化可的松; Cortisol
存儲(chǔ)條件:4°C,避光保存 *溶劑中:-80°C,6 個(gè)月;-20°C,1 個(gè)月(避光保存)
運(yùn)輸條件:美國大陸的室溫;其他地方可能有所不同。
產(chǎn)品活性:Hydrocortisone (Cortisol) 是腎上腺皮質(zhì)分泌的類固醇激素或糖皮質(zhì)激素。
細(xì)胞實(shí)驗(yàn):將細(xì)胞接種于膠原蛋白IV包被的Transwell小室上,用于六孔板(直徑24mm,膜材料:聚對(duì)苯二甲酸乙二醇酯(PET),0.4μm孔徑,孔密度1.6×106cm2),密度為每孔2.5×104細(xì)胞cm2。當(dāng)它們?cè)诘?天達(dá)到匯合時(shí),將不同的實(shí)驗(yàn)組細(xì)胞轉(zhuǎn)移到含有少量FCS的分化培養(yǎng)基中,并根據(jù)指示用TNFα或氫化可的松處理。MCE尚未獨(dú)立證實(shí)這些方法的準(zhǔn)確性。它們僅供參考。
IC50 & Target:Human Endogenous Metabolite
熱銷產(chǎn)品:CPTH2 | Pirinixic acid | Deoxycholic acid | Deferasirox | Methyl cellulose | Fibronectin, Human | Coenzyme Q10 | 5-Aminosalicylic Acid | GIP, human (TFA) | Campesterol
Trending products:Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
參考文獻(xiàn):
[1]. F?rster C, et al. Differential effects of hydrocortisone and TNFalpha on tight junction proteins in an in vitro model of the human blood-brain barrier. J Physiol. 2008 Apr 1;586(7):1937-49.
[2]. Bellinghausen I, et al. Inhibition of human allergic T-cell responses by IL-10-treated dendritic cells: differences from hydrocortisone-treated dendritic cells. J Allergy Clin Immunol. 2001 Aug;108(2):242-9.
[3]. Chappell D, et al. Hydrocortisone preserves the vascular barrier by protecting the endothelial glycocalyx. Anesthesiology. 2007 Nov;107(5):776-84.
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