目錄:MedChemExpress LLC>>信號(hào)通路>> ISO-1 | MedChemExpress
| 參考價(jià) | ￥ 1045 |
| 參考價(jià) | ￥ 1045 |
更新時(shí)間：2023-09-28 14:53:31瀏覽次數(shù)：137評(píng)價(jià)
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| CAS | 478336-92-4 | 純度 | 99.64% |
|---|---|---|---|
| 分子量 | 235.24 | 分子式 | C??H??NO? |
| 供貨周期 | 現(xiàn)貨 | 規(guī)格 | 10 mM * 1 mL |
| 貨號(hào) | HY-16692 | 應(yīng)用領(lǐng)域 | 醫(yī)療衛(wèi)生,化工,生物產(chǎn)業(yè),制藥 |
MCE 的所有產(chǎn)品僅用作科學(xué)研究或藥證申報(bào)，我們不為任何個(gè)人用途提供產(chǎn)品和服務(wù)。
CAS No. : 478336-92-4
MCE 國(guó)際站：ISO-1
產(chǎn)品活性：ISO-1 是巨噬細(xì)胞移動(dòng)抑制因子(MIF) 拮抗劑，IC50 值為 7 μM。
研究領(lǐng)域：Immunology/Inflammation
作用靶點(diǎn)：Macrophage migration inhibitory factor (MIF)
In Vitro: ISO-1 (0.1-20 μM; 16 hours) has a slight inhibitory effect on Cox-2 secretion without the addition of recombinant MIF.
In Vivo: ISO-1 (injected intraperitoneally; 3.5-35 mg/kg; twice daily; 2 weeks) improves the survival rate from lethal endotoxemia and shows the anti-inflammatory effect.ISO-1 (intraperitoneal injection; 35 mg/kg; twice daily; 3 days) causes a significant reduction in average implant size and decreases Flk1 expression in implants.
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