SMA平滑肌肌動(dòng)蛋白（鼠單克隆抗體）Actin,Smooth Muscle

廣州健侖生物科技有限公司

微絲（microfilament，MF）又稱肌動(dòng)蛋白纖維，是普通存在于真核細(xì)胞中由肌動(dòng)蛋白（actin）組成的直徑為5~8nm的螺旋狀纖維。肌動(dòng)蛋白（actin）是一種中等大小的蛋白質(zhì)，由375-377個(gè)氨基酸殘基組成，并且是由一個(gè)大的、高度保守的基因編碼。它在生物界有廣泛的分布，除肌肉組織外，還存在于幾乎所有的真核細(xì)胞中，如人的腦組織，血小板和多種植物細(xì)胞，在很多菌類中也有發(fā)現(xiàn)。

SMA是一種標(biāo)記平滑肌的肌動(dòng)蛋白，可以與平滑肌肌動(dòng)蛋白α異構(gòu)體反應(yīng)，但不能識(shí)別來(lái)源于成纖維細(xì)胞、骨骼肌以及心肌的肌動(dòng)蛋白。

我司還提供其它進(jìn)口或國(guó)產(chǎn)試劑盒：登革熱、瘧疾、流感、A鏈球菌、合胞病毒、腮病毒、乙腦、寨卡、黃熱病、基孔肯雅熱、克錐蟲(chóng)病、違禁品濫用、肺炎球菌、軍團(tuán)菌、化妝品檢測(cè)、食品安全檢測(cè)等試劑盒以及日本生研細(xì)菌分型診斷血清、德國(guó)SiFin診斷血清、丹麥SSI診斷血清等產(chǎn)品。

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【產(chǎn)品介紹】

細(xì)胞定位：細(xì)胞漿

克隆號(hào)：1A4

同型：IgG/K

適用組織：石蠟/冰凍

陽(yáng)性對(duì)照：闌尾

抗原修復(fù)：熱修復(fù)（EDTA）

抗體孵育時(shí)間：30-60min

SMA平滑肌肌動(dòng)蛋白（鼠單克隆抗體）Actin,Smooth Muscle

疾病診斷
診斷標(biāo)準(zhǔn)
WHO專家會(huì)建議的診斷原則是：
1、從新鮮糞便標(biāo)本中查到吞噬有紅細(xì)胞的滋養(yǎng)體，或從腸壁活檢組織中查到滋養(yǎng)體是本病確診的可靠依據(jù)。
2、從糞便標(biāo)本中僅查到1-4個(gè)核包囊或腸腔型滋養(yǎng)體，應(yīng)報(bào)告為溶組織內(nèi)阿米巴、迪斯帕內(nèi)阿米巴感染。此時(shí)即使患者有癥狀，亦不能據(jù)此得出腸阿米巴病的診斷，應(yīng)根據(jù)流行病學(xué)史、血清抗體檢測(cè)、糞抗原檢測(cè)或PCR檢測(cè)證實(shí)感染蟲(chóng)株確屬溶組織內(nèi)阿米巴后，診斷才能確立。否則必須尋找引起腹瀉的其他原因。
3、在有癥狀患者的血清中若能查到高滴度的阿米巴抗體，亦是本病診斷的有力證據(jù)。
輔助檢查
1.糞便檢查：大便呈暗紅色，有糞質(zhì)，帶血、膿或粘液，呈腥臭。
2.乙狀結(jié)腸鏡檢查：如糞檢陰性，乙狀結(jié)腸鏡檢查有很大診斷價(jià)值。潰瘍常較表淺，、覆有黃色膿液。潰瘍邊緣略突出，稍見(jiàn)充血，自潰瘍面刮取材料作顯微鏡檢查，發(fā)現(xiàn)病原體的機(jī)會(huì)較多。
3.阿米巴肝膿腫：腹部B超檢查可見(jiàn)到病灶。
鑒別診斷
應(yīng)與其他原因引起的腸道疾病相鑒別，尤其是細(xì)菌性痢疾，尚有腸結(jié)核、血吸蟲(chóng)病、結(jié)腸炎、結(jié)腸癌及其他腸道原蟲(chóng)感染亦可與腸阿米巴病混淆。潰瘍病、膽囊病、結(jié)腸息肉等須與有不明確腹痛及腸出血者區(qū)別。綜合運(yùn)用以上診斷方法，鑒別不難。
疾病治療
1、一般治療：注意休息，進(jìn)食半流質(zhì)少渣高蛋白飲食。
2、病原治療：甲硝噠唑或稱滅滴靈：原是抗滴蟲(chóng)藥物，對(duì)侵襲組織的阿米巴滋養(yǎng)體有*的殺滅作用且較安全，適用于腸內(nèi)腸外各型的阿米巴病。劑量為600～800mg、口服、1日3次，連服5～10日；兒童為50mg/kg/日，分3次服，連續(xù)7日。服藥期間偶有抗原抗體、腹痛、頭昏、心慌，不需特殊處理。服藥期忌酒，因可引起精神錯(cuò)亂。孕婦3個(gè)月以內(nèi)及哺乳婦忌用。
疾病預(yù)后
腸阿米巴病及時(shí)治療后預(yù)后良好。如并發(fā)腸出血、腸穿孔和彌漫性腹腔炎以及有肝、肺、腦部轉(zhuǎn)移性膿腫者，預(yù)后差。
疾病預(yù)防
煮沸、過(guò)濾、消毒飲水，防止吃生菜及防止飲食的被污染，適當(dāng)處理糞便，防止蒼蠅孳生和滅蠅，均為重要措施。檢查和治療從事飲食業(yè)的排包囊者及慢性患者極為重要。
疾病護(hù)理
1.消化道隔離。
2.病情觀察：觀察大便的次數(shù)和形狀、顏色。
3.糞便標(biāo)本的采集需要注意：及時(shí)采集新鮮大便，挑選有粘液、膿血的部分及時(shí)送檢，并注意保溫。

我司還提供其它進(jìn)口或國(guó)產(chǎn)試劑盒：登革熱、瘧疾、流感、A鏈球菌、合胞病毒、腮病毒、乙腦、寨卡、黃熱病、基孔肯雅熱、克錐蟲(chóng)病、違禁品濫用、肺炎球菌、軍團(tuán)菌、化妝品檢測(cè)、食品安全檢測(cè)等試劑盒以及日本生研細(xì)菌分型診斷血清、德國(guó)SiFin診斷血清、丹麥SSI診斷血清等產(chǎn)品。

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【公司名稱】 廣州健侖生物科技有限公司
【市場(chǎng)部】    楊永漢

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【騰訊  】 
【公司地址】 廣州清華科技園創(chuàng)新基地番禺石樓鎮(zhèn)創(chuàng)啟路63號(hào)二期2幢101-103室

Disease diagnosis
Diagnostic criteria
The diagnostic principles that WHO experts recommend are:
1, found from the fresh stool specimens of phagocytizing red blood cell trophozoites, or from the intestinal wall biopsy found trophozoite is a reliable basis for the diagnosis of this disease.
2, only found from the stool specimens 1-4 nuclear cysts or gut trophozoites, should be reported as Entamoeba histolytica, disiphenase amoebic infection. At this point, even if the patient has symptoms, we can not conclude that the diagnosis of intestinal amoebiasis should be based on epidemiological history, serum antibody test, fecal antigen test or PCR test confirmed that infected worm indeed Entamoeba histolytica After the diagnosis can be established. Otherwise you have to look for other causes of diarrhea.
3, in patients with symptomatic sera if you can find high titers of amebic antibodies, is also a strong evidence of the diagnosis of the disease.
Auxiliary examination
1. stool examination: stool was dark red, fecal material, blood, pus or mucus, was stench.
2. sigmoidoscopy: such as fecal negative, sigmoidoscopy has great diagnostic value. More often superficial ulcers, covered with yellow pus. Ulcer slightly prominent edge, a little congestion, since the ulcer surface scrape the material for microscopic examination and found more chances of pathogens.
3. Amoeba liver abscess: Abdominal B-ultrasound can be seen lesions.
Differential diagnosis
Should be distinguished from other causes of intestinal diseases, especially bacillary dysentery, there are intestinal tuberculosis, schistosomiasis, colitis, colon cancer and other intestinal protozoa infections can also be confused with enteromoea. Canker disease, gallbladder disease, colon polyps, etc. must be with no clear abdominal pain and intestinal bleeding were the difference. Comprehensive use of the above diagnostic methods, identification is not difficult.
Disease treatment
1, the general treatment: pay attention to rest, eat less semi-liquid high protein diet.
2, the pathogen treatment: metronidazole or metronidazole: the original anti-trichomoniasis drugs, the invasion of the organization of amoeba trophozoites have a very strong role in the killing and safer, suitable for all types of intestinal Of amoebiasis. Dose 600 ~ 800mg, orally, 3 times a day, and even served 5 to 10 days; children 50mg / kg / day, 3 times for 7 consecutive days. Occasionally medication antigen antigen, abdominal pain, dizziness, palpitation, without special treatment. Take the medication bogey, because it can cause confusion. Pregnant women within 3 months and breastfeeding women hanged.
Disease prognosis
Good prognosis after timely treatment of intestinal amoebiasis. Such as complicated with intestinal bleeding, intestinal perforation and diffuse peritonitis and liver, lung, brain metastatic abscess, poor prognosis.
prevent disease
Boiling, filtration, disinfection of drinking water, to prevent eating lettuce and prevent contamination of the diet, proper disposal of manure, to prevent flies breeding and fly, are important measures. It is extremely important to examine and treat patients in the catering industry as well as chronic patients.
Disease care
1. Digestive tract isolation.
2. Disease observation: observe the number of stool and shape, color.
3. Need to pay attention to the collection of stool specimens: timely collection of fresh stool, the selection of mucus, pus and blood part of the timely submission, and pay attention to insulation.