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SW 780 人膀胱移行細(xì)胞癌返回列表頁(yè)

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人膀胱移行細(xì)胞癌SW 780

種屬	人
別稱	SW-780; SW 780
組織來(lái)源	膀胱
疾病	膀胱癌
傳代比例/細(xì)胞消化	1:2傳代，消化2-3分鐘
培養(yǎng)基配置	Leibovitz's L-15培養(yǎng)基；10%胎牛血清；1%雙抗
簡(jiǎn)介	SW 780細(xì)胞是由A· Leibovitz在1974年從期移行細(xì)胞瘤中建立的細(xì)胞株，該患者接受過(guò)術(shù)前(Thiotepa)；報(bào)道稱該細(xì)胞的植板率為41%
形態(tài)	上皮細(xì)胞樣
生長(zhǎng)特征	貼壁生長(zhǎng)
倍增時(shí)間	~38h
致瘤性	Yes, forms tumors in nude mice.
STR	CSF1PO 10,11 D3S1358 16,18 D5S818 11,12 D7S820 9,10 D8S1179 13 D13S317 11,12 D16S539 9,11 D18S51 15 D21S11 29,30 FGA 19,20 Penta D 9 Penta E 12 TH01 6 TPOX 8 vWA 16
保藏機(jī)構(gòu)	ATCC; CRL-2169
備注	該細(xì)胞推薦使用Leibovitz's L-15培養(yǎng)基，無(wú)二氧化碳培養(yǎng)。

Microsatellite instability, Epstein-Barr virus, PD-L1 expression, and tumor mutational burden are now regarded as potent predictive markers for immunotherapy in patients with GC. Novel immunotherapy and combination therapy targeting new immune checkpoint molecules such as lymphocyte-activation gene 3, T cell immunoglobulin, and mucin domain containing-3, and indoleamine 2,3-dioxygenase have been suggested,
stimulation with twelve immunomodulators including immune checkpoint inhibitors (ICI) in 43 human primary tumors. This 'in sitro' (in situ/in vitro) assay has the potential to predict unresponsiveness to anti-PD-1 mAbs, and