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當(dāng)前位置:BPS Bioscience Inc.>>Cell Signaling Pathway Cell Lines>> 60513ARE Luciferase Reporter HepG2 Cell Line (Nrf2 Antioxidant Pathway)

ARE Luciferase Reporter HepG2 Cell Line (Nrf2 Antioxidant Pathway)

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產(chǎn)品型號(hào)60513

品       牌BPS Bioscience

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更新時(shí)間:2024-11-26 15:42:12瀏覽次數(shù):202次

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●Purchase●DescriptionTheantioxidantresponseelement(ARE)LuciferaseReporterHepG2hepaticcelllinecontainsastablyintegratedfireflyluciferasereporterunderthecontrolofARE
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Description

The antioxidant response element (ARE) Luciferase Reporter HepG2 hepatic cell line contains a stably integrated firefly luciferase reporter under the control of ARE, which is recognized by the transcription factor Nuclear factor erythroid 2-related factor 2 (Nrf2). Luciferase expression correlates with activation of Nrf2 and the antioxidant pathway. This cell line was validated by stimulation with tert-butylhydroquinone, sulforaphane, and RTA-408 (omaveloxone).

Created with BioRender.com
Figure 1: Illustration of the ARE Luciferase Reporter HepG2 Cell Line (Nrf2 Antioxidant Pathway) mechanism.

This product has been cited 31 times.

Purchase of this cell line is for research purposes only; commercial use requires a separate license. View the full terms and conditions.

Synonyms
ARE cell line, Nrf2 reporter, Nrf, Hepg2, ARE

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